报告题目: Regulation of CD8 T-Cell Memory by the AKT-Fox-O Pathway

报告人:  Marulasiddappa Suresh 教授

报告地点: 动医动科大楼 B110 室

报告时间: 5月5日（星期四）上午10: 00-11: 00

: 索 勋  教授

联系人

 

报告人简介: Marulasiddappa Suresh，美国威斯康星大学教授。Virology、Journal of Veterinary Science、Frontiers in Microbiology编委。Journal of Immunology、Journal of Virology、Plos Pathogens、Nature Medicine等多种学术期刊的评阅人。曾获威斯康星大学兽医学院杰出校友研究奖。研究成果以第一或通讯作者的文章发表于Journal of Immunology、Plos Pathogens等著名杂志数十篇。

 

部分研究论文：

 

Nanjappa, S. G, E. H. Kim, and M. Suresh (2011) Immunotherapeutic effects of IL-7 during a chronic viral infection in mice. Blood 117(19):5123-32.

Sullivan, J. A., E. H. Kim, E. Plisch, S. L. Peng, and M. Suresh (2012) FOXO3 regulates CD8 T cell memory by T cell-intrinsic mechanisms. PLoS Pathog. 8(2):e1002533. PMC3280979

Kim, E.H., J. S. Sullivan E. H. Plisch, M. M. Tejera, A. Jatzek, K. Y. Choi, and M. Suresh (2012) Signal integration by Akt regulates CD8 T cell effector and memory differentiation. J. Immunol. 188(9):4305-14; PMC3331885.

Sullivan, J. A., E.H. Kim, E. Plisch, and M. Suresh (2012) FOXO3 regulates the CD8 T cell response to a chronic viral infection. J. Virol. 86(17):9025-34. PMID: 22675000.

Jatzek, A., M. M. Tejera, A. Singh, J. A. Sullivan, E. H. Plisch and M. Suresh (2012) p27Kip1 negatively regulates the magnitude and persistence of CD4 T cell memory. J. Immunol. 189(11):5119-28.

Jatzek, A. M. M. Tejera, E.H. Plisch and M. Suresh (2013) T cell-intrinsic and extrinsic mechanisms of p27Kip1 in the regulation of CD8 T cell memory. Immunol. Cell Biol. 91(2):120-9 (OUTSTANDING OBSERVATION).

Tejera, M. M. E. H. Kim, J. A. Sullivan, E. H. Plisch and M. Suresh (2013) FoxO1 regulates the effector to memory transition and maintenance of functional CD8 T cell memory. J. Immunol. 191(1):187-99.

Kim, E. D. G. Gasper, E. Plisch, J. Svaren and M. Suresh (2014). Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease. J. Immunol. 192(3):985-95..

Gasper, D. G. M. M. Tejera and M. Suresh (2014). CD4 T cell memory: Generation and Maintenance. Crit. Rev. Immunol. 34(2):121-146.

Cheloha, R., J. A. Sullivan, T. Wang, J. M. Sand, J. Sidney, A. Sette, M. E. Cook, M. Suresh* and S. Gellman (2015) Consequences of Periodic α-to-β Residue Replacement for Immunological Recognition of Peptide Epitopes. ACS Chem Biol. 10(3):844-54. * Co-corresponding author.

Kim, E. H., B. Neldner, R. Craig and M. Suresh (2016) Mcl-1 regulates effector and

memory CD8 T-cell differentiation during acute viral infection. Virology. 490:75-82.

 

欢迎老师和同学参加！