教师简介

姓名：	刘佳利
性别：	男
系别：	动物学与动物生理学
职称：	副教授
学位：	博士

刘佳利 博士，副教授，博士生导师。现于中国农业大学生物学院动物生理系和畜禽生物育种全国重点实验室从事科研教学工作。

学习与工作经历

2016.9-2018.2,美国密歇根州立大学 生殖与发育生物学实验室，合作研究

2014.10-2016.4, 美国密歇根州立大学 生殖与发育生物学实验室，访问学者

2009.1-2010.1：意大利比萨大学 细胞与发育生物学实验室，访问学者

2007.12-至今 中国农业大学，副教授

2005.7-2007.12：中国农业大学, 讲师

2000.9-2005.7：中国农业大学，硕士，博士

1995.8-2000.7：辽宁省沈阳生物技术研究所 研究实习员

1991.9-1995.7：北京农业大学，本科

研究方向

 动物生殖与发育的调控机理

主讲课程

《动物生理学》（本科生）

《动物生理学实验》（本科生）

《生理学大实验及实验设计》（本科生）

《现代生命科学研究技术-免疫组织化学》（研究生） 

联系方式

电话：62732277

邮件：liujiali at cau.edu.cn

发表论文（“#”共同第一作者；“*”通讯作者）

1. Lv Z#, Sun L#, Xie X, Yao X, Tian S, Wang C, Wang F*, Liu J* (2024) TMEM225 is essential for sperm maturation and male fertility by modifying protein distribution of sperm in mice. Mol Cell Proteomics 23: 100720

2. Sun L, Lv Z, Chen X, Ye R, Tian S, Wang C, Xie X, Yan L, Yao X, Shao Y, Cui S, Chen J*, Liu J* (2024) Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice. eLife 12: RP89316

3. Yao X#, Wang C#, Yu W, Sun L, Lv Z, Xie X, Tian S, Yan L, Li L, Liu J* (2024) BCAS2 regulates oocyte meiotic prophase I by participating in mRNA alternative splicing. FASEB J 38: e23361

4. Yao X#, Wang C#, Yu W, Sun L, Lv Z, Xie X, Tian S, Yan L, Zhang H, Liu J* (2023) SRSF1 is essential for primary follicle development by regulating granulosa cell survival via mRNA alternative splicing. Cell Mol Life Sci 80: 343

5. Chen X#, Xie X#, Li J, Sun L, Lv Z, Yao X, Li L, Jin H*, Cui S*, Liu J* (2023) BCAS2 participates in insulin synthesis and secretion via mRNA alternative splicing in mice. Endocrinology 165: bqad152

6. Guo H#, Zhang D#, Zhou Y, Sun L, Li C, Luo X, Liu J*, Cui S* (2023) Casein kinase 1alpha regulates testosterone synthesis and testis development in adult mice. Endocrinology 164: bqad042

7. Liu J#, Hermo L#, Ding D#, Wei C, Mann JM, Yan X, Melnick AF, Wu Y, Withrow A, Cibelli J, Hess RA, Chen C* (2023) SYPL1 defines a vesicular pathway essential for sperm cytoplasmic droplet formation and male fertility. Nat Commun 14: 5113

8. Sun L#, Chen J#, Ye R, Lv Z, Chen X, Xie X, Li Y, Wang C, Lv P, Yan L, Tian S, Yao X, Chen C, Cui S, Liu J* (2023) SRSF1 is crucial for male meiosis through alternative splicing during homologous pairing and synapsis in mice. Sci Bull 68: 1100-4

9. Sun L#, Lv Z#, Chen X, Wang C, Lv P, Yan L, Tian S, Xie X, Yao X, Liu J, Wang Z, Luo H, Cui S, Liu J* (2023) SRSF1 regulates primordial follicle formation and number determination during meiotic prophase I. BMC Biol 21: 49

10. Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H*, Liu J* (2023) SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J 37: e22918

11. Yao X#, Wang C#, Sun L, Yan L, Chen X, Lv Z, Xie X, Tian S, Liu W, Li L*, Zhang H*, Liu J* (2023) BCAS2 regulates granulosa cell survival by participating in mRNA alternative splicing. J Ovarian Res 16: 104

12. Ding D#, Liu J#, Dong K, Melnick AF, Latham KE, Chen C* (2019) Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis. Nucleic Acids Res 47: 2594-2608

13. Wang Z, Gai Y, Zhou J, Liu J*, Cui S* (2019) miR-375 mediates the CRF signaling pathway to regulate catecholamine biosynthesis by targeting Sp1 in porcine adrenal gland. Stress 22: 332-346

14. Ding D#, Liu J#, Dong K#, Midic U, Hess RA, Xie H, Demireva EY, Chen C* (2017) PNLDC1 is essential for piRNA 3' end trimming and transposon silencing during spermatogenesis in mice. Nat Commun 8: 819

15. Zhao J, Zhao J, Xu G, Wang Z, Gao J, Cui S, Liu J* (2017) Deletion of Spata2 by CRISPR/Cas9n causes increased inhibin alpha expression and attenuated fertility in male mice. Biol Reprod 97: 497-513

16. Wang S#, Liu J#, Li X, Ji X, Zhang J, Wang Y, Cui S* (2016) MiR-125b Regulates Primordial Follicle Assembly by Targeting Activin Receptor Type 2a in Neonatal Mouse Ovary. Biol Reprod 94: 83

17. Liu S, Liu Y, Ma Q, Cui S, Liu J* (2015) Expression and localization of cysteine sulfinate decarboxylase in major salivary glands of male mice. Arch Oral Biol 60: 615-21

18. Cao W#, Chen W#, Liang X, Zhou J, Wei C, Cui S, Liu J* (2014) All-trans-retinoic acid ameliorates the inflammation by inducing transforming growth factor beta 1 and interleukin 10 in mouse epididymitis. Am J Reprod Immunol 71: 312-21

19. Chen J, Fu R, Cui Y, Pan J, Li Y, Zhang X, Evans SM, Cui S, Liu J* (2014) LIM-homeodomain transcription factor Isl-1 mediates kisspeptin's effect on insulin secretion in mice. Mol Endocrinol 28: 1276-90

20. Sun D, Cui T, Luo H, Li R, Cui S, Liu J* (2012) Cell-specific distributions of estrogen receptor alpha (ERalpha) and androgen receptor (AR) in anterior pituitary glands from adult cockerels as revealed by immunohistochemistry. Cell Tissue Res 348: 551-8

21. Fu R#, Liu J#, Fan J, Li R, Li D, Yin J*, Cui S* (2012) Novel evidence that testosterone promotes cell proliferation and differentiation via G protein-coupled receptors in the rat L6 skeletal muscle myoblast cell line. J Cell Physiol 227: 98-107

承担项目及课题

已结题国家重点研发项目子课题1项，国家自然科学基金面上项目2项，教育部留学回国人员启动基金1项，横向课题3项。

现主持国家重点研发项目子课题1项，国家自然科学基金面上项目1项，北京自然基金面上项目1项。

社会兼职

中国畜牧兽医学会动物生理生化分会常务理事