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于静娟
发布日期：2018-09-14 浏览次数：　　信息来源：生物学院

教师简介

姓名：于静娟            
性别：女
系别：生物化学与分子生物学
职称：教授
学位：博士











于静娟 博士，三级教授。1990年在北京农业大学获得理学学士学位，1996年在中国农业大学获得理学博士学位。1998-1999年在韩国浦项工科大学（Pohang University of Science and Technology）生命科学系Youngsook Lee教授研究室从事博士后研究。2008年作为高级访问学者在美国亚利桑那大学（The University of Arizona）植物系Brian A. Larkins教授研究室从事玉米种子胚乳发育的研究。2005年入选教育部新世纪人才支持计划。2016年获得 “宝钢教学基金优秀教师奖”荣誉称号。近年来在JXB, PMB，PNAS，Planta，BMC Plant Biology，Frontiers in Plant Science 等国际杂志上发表研究论文二十余篇。

 

学习与工作经历

1986/09－1990/06，北京农业大学，理学学士学位

1990/09－1993/06，中国农业大学，理学硕士学位

1993/02－1996/06，中国农学大学，理学博士学位

1998/08－1999/10，韩国浦项工科大学，博士后

2008/02－2008/08，美国亚利桑那大学，高访

2005/12－至今，中国农业大学生物学院，教授

2005年入选教育部新世纪人才支持计划


研究方向

玉米和谷子发育和逆境相关基因的功能及表达调控、玉米品质改良基因工程和谷子功能基因组学的研究。

 

主讲课程

主讲本科生核心课《分子生物学实验》、《植物基因工程实验技术》和必修课《植物转基因技术》，主讲研究生《酶学与代谢调控》、《植物细胞工程》、《现代生命科学研究技术-Northern 杂交》和参讲研究生《植物遗传改良基因工程》

 

联系方式

电话：010-62733462办公/手机13641268609
邮件：yujj at cau.edu.cn
通讯地址：北京市海淀区圆明园西路2号中国农业大学西校区生命科学研究中心3027

 

发表文章 (*通讯作者，#共同第一作者)

  1. Li SX, Zhao Q, Zhu DY, Yu JJ*（2018）A DREB-Like transcription factor from Maize (Zea mays), ZmDREB4.1, plays a negative role in plant growth and development. Front. Plant Sci. 04 April https://doi.org/10.3389/fpls.2018.00395

  2. Peng J, Qi X, Chen XY, Li N, Yu JJ*（2017）ZmDof30 negatively regulates the promoter activity of the pollen-specific gene Zm908. Front. Plant Sci. 01 May  https://doi.org/10.3389/fpls.2017.00685

  3. Xiao WH, Yang Y, Yu JJ*（2017）ZmNST3 and ZmNST4 are master switches for secondary wall deposition in maize (Zea mays L.). Plant Science http://dx.doi.org/10.1016 /j.plantsci .2017.03.012

  4. Li JR, Dong Y, Li Cong, Pan YL, Yu JJ*（2017）SiASR4, the Target Gene of SiARDP from Setaria italica, Improves Abiotic Stress Adaption in Plants. Front. Plant Sci., 12 January 2017 | https://doi.org/10.3389/fpls.2016.02053

  5. Qi X, Li S, Zhu Y, Zhao Q, Zhu DY, Yu JJ*（2017）ZmDof3, a maize endosperm-specific Dof protein gene, regulates starch accumulation and aleurone development in maize endosperm. Plant Mol Biol  93: 7. doi:10.1007/s11103-016-0543-y

  6. Pan YL, Li JR, Jiao LC, Li C, Zhu DY, Yu JJ*（2016）A Non-specific Setaria italica lipid transfer protein gene plays a critical role under abiotic stress. Front. Plant Sci., 24 November | https://doi. org/10.3389/fpls.2016.01752

  7. LiuYW, Xie SJ, Yu JJ*（2016）Genome-wide analysis of the lysine biosynthesis pathway network during maize seed development. PLOS ONE  DOI:10.1371/journal.pone.0148287

  8. Yi F, Chen J, Yu JJ*（2015）Global analysis of uncapped mRNA changes under drought stress and microRNA-dependent endonucleolytic cleavages in foxtail millet. BMC Plant Biology 15:241

  9. Liu C, Li SX, Yue J, Xiao WH, Zhao Qian, Zhu DY, Yu JJ*（2015）Microtubule- associated protein SBgLR facilitates storage protein deposition and its expression leads to lysine content increase in transgenic maize endosperm. Int. J. Mol. Sci. 16: 29772–29786;

  10. Pan YL, Ma X, Liang HW Liang, Zhao Q, Zhu DY, Yu JJ*（2015）Spatial and temporal activity of the foxtail millet (Setaria italica) seed-specific promoter pF128. Planta 241: 57–67.

  11. Wang MZ, Li P, Li C, Pan YL, Jiang XY, Zhu DY, Zhao Q, Yu JJ*（2014）SiLEA14, a novel atyptical LEA protein, confers abiotic stress resistance in foxtail millet. BMC Plant Biology 14: 290

  12. Yue J, Li C, Liu YW, Yu JJ*（2014）A remorin gene SiREM6, the target gene of SiARDP, from foxtail millet (Setaria italica) promotes high salt tolerance in transgenic Arabidopsis. Plos One 6 (7): e100772

  13. Li C, Yue J, Wu XW, Xu C, Yu JJ*（2014） An ABA-responsive DRE-binding protein gene from Setaria italica, SiARDP, the target gene of SiAREB, plays a critical role under drought stress. Journal of Experimental Botany 65 (18): 5415-5 427

  14. Yue J, Li C, Zhao Q, Zhu DY and Yu JJ *（2014）Seed-specific expression of a lysine-rich protein gene, GhLRP, from cotton significantly increases the lysine content in maize seeds. Int. J. Mol. Sci. 15: 5350-5365; doi:10.3390/ijms15045350

  15. Dong X; Wang DX, Liu P, Li CX, Zhao Q, Zhu DY, Yu JJ*（2013）Zm908p11, encoded by a short open reading frame (sORF) gene, functions in pollen tube growth as a profilin ligand in maize. Journal of Experimental Botany 64: 2359-2372

  16. Yi F, Xie SJ, Liu YW, Di X and Yu JJ*（2013） Genome-wide characterization of microRNA in foxtail millet (Setaria italica). BMC Plant Biology 13:212

  17. Qi X, Xie SJ, Liu YW, Yi F, Yu JJ*（2013）Genome-wide annotation of genes and noncoding RNAs of foxtail millet in response to simulated drought stress by deep sequencing. Plant Mol Biol. 83:459-473

  18. Liu C, Qi X, Zhao Q, Yu JJ*（2013） Characterization and Functional Analysis of the Potato Pollen-Specific Microtubule-Associated Protein SBgLR in Tobacco. PLoS ONE 8 (3): e60543. doi:10.1371/journal.pone.0060543.

  19. Wang MZ, Liu C, Li SX, Zhu DY, Zhao Q, Yu JJ*（2013）Improved nutritive quality and salt resistance in transgenic maize by simultaneously overexpression of a natural lysine-rich protein gene, SBgLR, and an ERF transcription factor gene, TSRF1. Int. J. Mol. Sci. 14, 9459-9474; doi:10.3390/ ijms14059459

  20. Sabelli PA, Liu Y, Dante RA, Lizarraga LE, Nguyen HN, Brown SW, Klingler JP, Yu JJ, LaBrant E, Layton TM., Feldman M, Larkins BA（2013）Control of cell proliferation, endoreduplication, cell size, and cell death by the retinoblastoma- related pathway in maize endosperm. Proc. Natl. Acad. Sci. USA. www.pnas.org/cgi/doi/10.1073/pnas. 1304903110

  21. Kang MM, Zhao Q, Zhu DY, Yu JJ*（2012）Characterization of microRNAs expression during maize seed development. BMC genomics 13: 360-371

  22. Chen XY, Wang DX, Liu C, Wang MZ, Wang T, Zhao Q, Yu JJ*（2012） Maize transcription factor Zmdof1 involves in the regulation of Zm401 gene. Plant Growth Regul 66: 271–284

  23. Wang MZ, Pan YL, Li C, Liu C, Zhao Q, Ao GM and Yu JJ*（2011） Culturing of immature inflorescences and Agrobacterium-mediated transformation of foxtail millet (Setaria italica). African Journal of Biotechnology 10 (73): 16466-16479

  24. Wang BS, Yu JJ, Zhu DY, Zhao Q（2011）Maize defensin ZmDEF1 is involved in plant response to fungal phytopathogens. African Journal of Biotechnology 10 (72): 16128-16137

  25. Luan YX, Wang BS, Zhao Q, Ao GM, Yu JJ*（2010）Ectopic expression of foxtail millet Zip-like gene, SiPf40, in transgenic rice plants causes a pleiotropic phenotype affecting tillering, vascular distribution and root development. Chinese Science-- Life Sciences 151 (11): 1-9

  26. Wang MY, Xu QY, Yu JJYuan M （2010） The putative Arabidopsis zinc transporter ZTP29 is involved in the response to salt stress. Plant Molecular Biology 73(4-5): 467-79

  27. Zhou P, Yang F, Yu JJ, Ao GM, Zhao Q （2010） Several cis-elements including a palindrome involved in pollen-specific activity of SBgLR promoter. Plant Cell Reports 29:503–511

  28. Xu YG, Wang BS, Yu JJ, Ao GA, Zhao Q（2010） Cloning and characterization of ZmZLP1, a gene encoding an endoplasmic reticulum-localized zinc transporter in Zea mays. Functional Plant Biology 37: 194-205.

  29. Wang DX, Li CX, Zhao Q, Zhu DY, Ao GM and Yu JJ*（2009）Zm401p10, encoded by an anther-specific gene with short open reading frames, is essential for tapetum degeneration and anther development in maize. Functional Plant Biology 36:73-85

  30. Zhao LN, Liu FX, Xu WY, Di C, Zhou SX, Yu JJ*, Su Z*（2009）Increased expression of OsSPX1 enhanced cold/subfreezing tolerance in tobacco and Arabidopsis thaliana. Plant Biotechnology Journal 7:550-561

  31. Xu XP, Zhu DY , Zhao Q, Ao GM, Ma CL and Yu JJ*.（2009）RNA silencing generated by directed repeats in maize. Molecular Biotechnology  41 (3): 213-223

  32. Zhao LN, Zhao Q, Ao GM, Yu JJ*（2009）The foxtail millet Si69 gene is a Wali7 (wheat aluminum induced protein 7) homologue and may function in aluminum tolerance. Chinese Science Bulletin 54(10): 1697-1706

  33. He XY, Tang MZH, Luo YB, Li X, Cao SSH, Yu JJ, Delaney B, Huang KL（2009）A 90-day toxicology study of transgenic lysine-rich maize grain (Y642) in Sprague-Dawley rats. Food and Chemical Toxicology 47:425-432

  34. Prommee W, Wang M, Zhao Q, Ao GM, Yu JJ*（2009） Efficient Agrobacterium- mediated transformation of maize using embryogenic callus. Chinese Journal of Biochemistry & Molecular Biology 25 (11): 1010-1016

  35. Liu YH, Feng XY, Xu YG, Yu JJ, Ao GM, Peng ZHY, Zhao Q (2009) Overexpression of millet ZIP-like gene (SiPf40) affects lateral bud outgrowth in tobacco and millet. Plant Physiology and Biochemistry 47: 1051-1060

  36. Li B, YU JJ, Zhao Q, Zhu DY, AO GM （2009）Transformation of the gene pf40 in maize. Scientia Agricultura Sinica 42 (9): 3334-3338 (in Chinese)

  37. Ma JX , Yan BX, Qu YY, Qin FF, Yang YT, Hao XJ, Yu JJ, Zhao Q, Zhu DY, Ao GM * （2008）Zm401, a short-open reading-frame mRNA or noncoding RNA, is essential for tapetum and microspore development and can regulate the floret formation in maize. J. Cellular Biochemistry 105 (1): 136-146.

  38. Qin FF, Zhao Q, Ao GM, Yu JJ*（2008）Co-Suppression of Si401, a maize pollen specific zm401 homologous gene, results in aberrant anther development in foxtail millet. Euphytica 163:103-111

  39. Lang ZH, Zhou P, Yu JJ, Ao GM, Zhao Q（2008）Functional characterization of the pollen-specific SBgLR promoter from potato (Solanum tuberosum L.). Planta 227:387-396.

  40. Li Q H, Hong B, Tong ZH, Yang Y J, Ma CH, Yu J J, Gao J P（2008）Establishment of Regeneration System and Transformation of Zm401 Gene in Lilium longiflorum× L.formosanum.(J). Journal of Agricultural Biotechnology 16(1):96-102 (in Chinese)。

  41. Xu X, Wu M, Zhao Q, Li R, Chen J, Ao G and Yu J*（2007）Designing and transgenic expression of melanin gene in tobacco trichome and cotton fiber. Plant Biology 9: 41-48.

  42. Dai XY, Yu JJ*, Ao GM, Zhao Q（2007）Overexpression of Zm401, an mRNA-like RNA, has distinct effects on pollen development in maize. Plant Growth Regulation 52: 229-239.

  43. Liu YH, Yu JJ, Ao GM, Zhao Q（2007）Factors influencing Agrobacterium-mediated transformation of foxtail millet. Chinese J. Biochemistry and Molecular Biology 23 (7): 531-536.

  44. Yang CH, Yu JJ, Zhao Q, Zhu DY, Ao GM （2007）Influence of maize LC regulatory gene on flower color of transgenic tobacco and petunia. J. Agricultural Biotechnology 15 (1): 85-89

  45. Zhao Y, Zhao Q, Ao GM, Yu JJ*（2006）Characterization and functional analysis of a pollen-specific gene st901 in Solanum tuberosum. Planta 224 (2): 405-412.

  46. Han Y ZH#, Yu JJ#, Guo FL and Watkins SC （2006）Polysomes are associated with microtubules in fertilized eggs of Chinese pine (Pinustabulaeformis). Protoplasma 227: 223-227.

  47. Wang DX, Zhao Q, Zhu DY, Ao GM, Yu JJ *（2006）Particle-bombardment- mediated co-transformation of maize with a lysine rich protein gene (sb401) from potato. Euphytica 150: 75-85.

  48. Ma JX, Zhao Q, Yu JJ* , Ao GM （2005）Ectopic expression of a maize pollen specific gene, zm401, results in aberrant anther development in tobacco. Euphytica 144: 133–140.

  49. Liu YH, Yu JJ, Zhao Q, Ao GM（2005）Genetic Transformation of millet (Tetaria italica) by Agrobacterium-mediated. Journal of Agricultural Biotechnology 13 (1): 32-37 (in Chinese).

  50. Xia YF, Zhao Q, Yu JJ, Ao GM（2005） Study of subcellular localization of PF40. Pro. Biochem. Biophys 31:1020-1025 (in Chinese)

  51. Yu JJ, Peng P, Zhang XJ ,Zhao Q, Zhu DY, Sun XH, Liu JQ, Ao GM （2004）Seed-specific expression of a lysine rich protein sb401 gene significantly increase both lysine and total protein content in maize seeds. Molecular Breeding 14:1-7.

  52. Dai XY, YuJJ*, Zhao Q, Zhu DY, Ao GM（2004）Non-coding RNA for ZM401, a pollen-specific gene of Zea mays. Acta Botanica Sincia 46 (4):497-504.

  53. Xue J, Yu JJ*, Zhao Q, Zhu DY, Ao GM（2004）Cloning and characterization of f103 in Setaria italica. J. China Agri. Univ. 99 (1):7-10 (in Chinese).

  54. Xue J, Yu JJ*, Zhao Q, Zhu DY, Ao GM（2004）Cloning and characterization of seed-specific expression gene f128 in Setaria italica. Journal of Agricultural Biotechnology  12 (5): 487-492 (in Chinese).

  55. Wang WM, Zhao Q, Zhu DY, Yu JJ*, Ao GM（2004）Transfer of high lysine gene and bar gene into rice by microprojectile bombardment and detection of their transgenic plants. Journal of Agricultural Biotechnology 12 (4): 363-368 (in Chinese).

  56. Lang ZH, Zhao Q, Yu JJ, Zhu DY, Ao GM（2004）Cloning of potato SBgLR gene and its intron splicing in transgenic maize. Plant Science 166 (5): 1227-1233.

  57. Lang ZH, Yu JJ, Zhu DY, Zhao Q, Ao GM（2004）Cloning of a lysine-rich gene SBgLR and the effect of improving the protein and lysine content in transgenic maize seed. Journal of Agricultural Biotechnology 12 (5): 487-492 (in Chinese)

  58. Zhang GP, Yu JJ, Zhu DY, Ao GM, Zhao Q (2004) Effects of the foreign gene encoding a lysine rich protein on protein compositions in transgenic maize grain. Scientia Agricultura Sinica, 37 (12): 1946-1950 (in Chinese).

  59. Zhao Q, Lai F, Yu JJ, Zhu DY, Ao GM（2004）Cloning of lycopene β-cyclase gene from millet (Setaria italica) related to carotenoid biosynthetic pathway. J. China Agri. Univ. 99 (1): 1-6 (in Chinese).

  60. Zhao Q, Yu JJ, Zhu DY, Ao GM（2004）Cloning and characterization of a pollen –specific lysine-rich protein cDNA (tsb) from tomato. Chinese J. of Biochemistry and Molecular Biology 20 (2): 275-279 (in Chinese).

  61. Zhao Q, Yu JJ, Zhu DY, Ao GM（2004）Improving free lysine content of maize by changing regulatory activities of aspartokinase and dihydrodipicolinate synthase.  Journal of Agricultural Biotechnology 12 (3): 247-252 (in Chinese).

  62. Zhang WH, Zhao Q, Yu JJ, Zhu DY, Ao GM（2003）To obtain transgenic maize plants with rabbit defensin (NP-1) gene and analyze their disease resistance. Journal of Agricultural Biotechnology 11 (4): 342-346 (in Chinese).

  63. Feng XY, Yu JJ, Zhao Q, Ao GM（2003） Cloning and characterization of a Setaria italica lipid transfer protein cDNA. Journal of Agricultural Biotechnology 11 (1): 11-15 (in Chinese).

  64. Sun XH, Ao GM, Yu JJ, Zhao Q（2001）Transfer of high lysine gene into maize inbred lines and the detection of transgenic plants. Journal of Agricultural Biotechnology 9 (2): 156-158 (in Chinese)

  65. Li CX, Liu JQ, Yu JJ, Zhao Q, Ao GM（2001）Cloning and expression analysis of pollen-specific cDNA ZM401 from Zea mays. Journal of Agricultural Biotechnology  9 (4): 374-377 (in Chinese)

  66. Fu Y F, Zhao D G, Han Y ZH, Yu J J, Meng F J（孟繁静）（2001）Floral homeotic gene FBP2 regulates the expression of peroxidase in leaves[J]. Acta Phytophysiologica Sinica 26(4) :293-296 (in Chinese with English abstract) .

  67. Yu JJ, Guo FL, Zhao DG, Fu YF, Han YZ, Ao GM, Meng FJ（1999）Cloning of the homeotic gene fbp2 from petunia hybrida and its effects in tobacco flower. Acta Botanica Sincia 41 (1): 45-50 (in Chinese).

  68. Zhang XJ, Liu J, Zhao Q, Yu JJ, Ao G（1999）Introduction of lysine-rich protein gene into maize by microprojectile bombardment and identification of transgenic plants. Chinese J. Agri. Biotech. 7: 363-367 (in Chinese).

  69. Yu JJ, Meng FJ（1998）Zearalenone and sex expression of hemp. J. China Agri. Univ.5: 24-28 (in Chinese).

  70. Yu JJ, Ao GM（1997）Expression of 10 kD sulfur-rich prolamin gene of rice in potato. Acta Botanica Sincia 39 (4): 329-334 (in Chinese).

  71. Yu JJ, Xu NF, Meng FJ（1997） Study of stamen specific protein of hemp. J. China Agri. Univ. 2 (3): 78 (in Chinese).

  72. Yu JJ, Ao GM（1993）Isolation and sequencing of a sulfur-rich 10 kd prolamin gene from rice seeds. J. Agricultural Biotechnology 1 (1): 38-42 (in Chinese).

 

获奖情况

2015年校优秀共产党员

2016年度校优秀教师。

2016年度宝钢教育基金优秀教师奖。

2018年校级优秀党务工作者

 

承担项目及课题

教育部新世纪人才支持计划（2006-2008）玉米花粉发育机制的研究

国家自然科学基金面上项目（2007-2009）玉米Dof蛋白对花粉特异Zm401 基因的表达调控

国家自然科学基金面上项目（2010-2012）具sORF基因Zm908 在玉米花粉发育中的作用机制

国家自然科学基金面上项目（2016-2019）转录因子Dof3在玉米籽粒糊粉层发育中的功能与作用机制

国家转基因重大专项（2009-2010）谷子抗旱耐逆相关基因克隆及分析

国家转基因重大专项（2008-2015）高赖氨酸高蛋白优质转基因玉米培育

国家转基因重大专项（2016-2020）高赖氨酸优质转基因玉米培育

863项目（2008-2010）谷子转基因技术建立与目标基因转化

973课题（2012-2016）能源高粱等能源植物选择性培育及遗传学的基础研

 

专利情况

高赖氨酸蛋白基因以及提高禾本科作物种子中赖氨酸和蛋白质含量的方法  ZL011182962 第二发明人

一种种子特异性高效启动子及其应用ZL2007100991697 第一发明人

一种花药绒毡层和花粉特异性高效启动子及其应用Zl2009100803517第一发明人

一种高赖氨酸蛋白基因GhLRP及其应用Zl2013103981029 第一发明人

谷子SiLEA14基因及应用ZL2014102008775 第一发明人

 

社会兼职

曾任中国生物化学与分子生物学会农学分会第一届理事会理事，副秘书长；第二届理事会常务理事、副秘书长。现任第四届理事会常务理事、副秘书长。中国生物化学与分子生物学会农业分会第一届教学委员会教主任委员。全国生物技术职业教育教学指导委员会下设农业生物技术职业教育教学指导委员会委员。《BMC Plant Biology》编委。

 
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