教师简介

姓名：	周文焜
性别：	男
系别：	植物科学
职称：	教授
学位：	博士

　　周文焜，教授，博士生导师，2013年博士毕业于中国科学院遗传与发育生物学研究所，2014-2019年在荷兰瓦赫宁根大学植物发育生物学系从事博士后研究，2020年以“杰出人才”引进中国农业大学生物学院，任教授，入选中国农业大学人才培育发展支持计划青年新星A类，2021年入选海外高层次人才引进计划青年项目（获优先资助），研究方向为植物根系生长可塑性与逆境应答。学术成果发表于Cell、Nature、Developmental Cell、EMBO J、PNAS、Plant Cell、Molecular Plant、New Phytologist、JIPB等国际主流学术期刊，其中第一/通讯作者文章11篇，主持国家自然科学基金面上项目2项，主持国家重点研发计划子课题等国家级项目，任Molecular Plant Feature editor，参与Molecular Plant、New Phytologist、Plant Communications、Plant Physiology、JIPB等国际学术期刊同行评审工作。

学习与工作经历

2020.04- 今，中国农业大学，生物学院植物科学系，教授

2014.04- 2019.12, 荷兰瓦赫宁根大学, 植物发育生物学系，博士后

2013.01- 2014.03，中国科学院遗传与发育生物学研究所，研究助理

2006.09- 2013.01，中国科学院遗传与发育生物学研究所，博士

2002.09- 2006.06，浙江大学，生命科学学院，学士

研究方向

　　植物固着生长的特点决定了其必须通过对生长发育的改变以适应不断变化的环境条件。因此，植物显示出惊人的生长发育可塑性。我们主要以模式植物和作物玉米根系作为研究对象，通过细胞生物学，遗传学，生物化学，生理学和分子生物学等技术手段，研究植物根系生长可塑性及根干细胞响应损伤等生物/非生物胁迫的再生调控机理。我们通过研究干细胞感受逆境信号进而调整生长发育进程的分子机理，以打破植物抗逆反应和生长发育的负相关，为作物高产高抗遗传改良提供理论指导和技术借鉴。 

联系方式

电话：010-62732678

邮件：zhouwenkun at cau.edu.cn

通讯地址：北京海淀区圆明园西路 2 号，中国农业大学生物学院，100193

发表文章 (#corresponding author, *co-first author)

1. Chen C ^#, Hu Y^#, Ikeuchi M^#, Jiao Y^#, Prasad K^#, Su Y^#, Xiao J^#, Xu L^#, Yang W^#, Zhao Z^#, Zhou W^#, Zhou Y^#, Gao J, and Wang J^#. (2024). Plant regeneration in the new era: from molecular mechanisms to biotechnology applications. Sci China Life Sci, 67: 1338-1367.

2. Zaragoza J, Klap K, Heidstra R, Zhou W, and Scheres B^# (2024) The dual role of the RETINOBLASTOMA-RELATED protein in the DNA damage response is coordinated by the interaction with LXCXE-containing proteins. Plant J. 118, 1194-1206. 10.1111/tpj.16665.

3. Ren, Y.Y., Jiang, M.D., Zhu, J.K., Zhou, W.K., and Zhao, C.Z^#. (2024). Simultaneous mutations in ITPK4 and MRP5 genes result in a low phytic acid level without compromising salt tolerance in Arabidopsis. Journal of Integrative Plant Biology. Doi: https://doi.org/10.1111/jipb.13745.

4. Zeng J, Geng X, Zhao Z^#, and Zhou W^#. (2024). Tipping the balance: The dynamics of stem cell maintenance and stress responses in plant meristems. Curr Opin Plant Biol, 78: 102510. doi:https://doi.org/10.1016/j.pbi.2024.102510.

5. Hao R, Zhou W^#, Li J, Luo M, Scheres B, and Guo Y^#. (2023). On salt stress, PLETHORA signalling maintains root meristems. Dev Cell, 18:1657-1669. doi:https://doi.org/10.1016/j.devcel.2023.06.012.

6. Guarneri N, Willig JJ, Sterken MG, Zhou WK, Hasan MS, Sharon L, Grundler FMW, Willemsen V, Goverse A, Smant G, and Lozano-Torres, JL^#. (2023). Root architecture plasticity in response to endoparasitic cyst nematodes is mediated by damage signaling. New Phytol, 237: 807-822. 10.1111/nph.18570.

7. Zhou W^# and Zhang X. (2022). Small bending, big curvature. J Integr Plant Biol, 64: 3-4. doi: https://doi.org/10.1111/jipb.13203.

8. Zhang G, Liu W, Gu Z, Wu S, E Y, Zhou W^#, Lin J^#, and Xu L^#. (2021). Roles of the wound hormone jasmonate in plant regeneration. J Exp Bot, erab508. doi: https://doi.org/10.1093/jxb/erab508.

9. Zhou W^#, and Zhang X. (2021). Molecular mechanism of Verticillium dahliae induced leaf senescence. Mol Plant 14: 1785-1786. doi: https://doi.org/10.1016/j.molp.2021.08.020.  

10. Zhou W^#. (2021). CIK receptor kinases in root meristem. Mol Plant 14: 873. doi: https://doi.org/10.1016/j.molp.2021.04.016.

11. Zhai H*, Zhang X*, You Y, Lin L, Zhou W^#, and Li C^#. (2020). SEUSS integrates transcriptional and epigenetic control of root stem cell organizer specification. EMBO J, 39:e105047. doi: https://doi.org/10.15252/embj.2020105047.

12. Zhou W, Lozano J, Blilou I, Zhang X, Zhai Q, Smant G, Li C and Scheres B^#. (2019). A jasmonate signaling network activates root stem cells and promotes regeneration. Cell, 177: 942-956. doi: https://doi.org/10.1016/j.cell.2019.03.006.

13. Zhang X*, Zhou W*^#, Chen Q*^#, Fang M, Zheng S, Scheres B and Li C^#. (2018). Mediator subunit MED31 is required for radial patterning of Arabidopsis roots Proc. Nat. Acad. Sci. USA, 115: E5624-E5633. doi: https://doi.org/10.1073/pnas.1800592115.

14. Zhou W*, Wei L*, Xu J, Zhai Q, Jiang H, Chen R, Chen Q, Sun J, Chu J, Zhu L, Liu C-M and Li C^#. (2010). Arabidopsis tyrosylprotein sulfotransferase acts in the auxin/PLETHORA pathway in regulating postembryonic maintenance of root stem cell niche. Plant Cell, 22: 3692-3709. doi: https://doi.org/10.1105/tpc.110.075721.

15. Long Y, Stahl Y, Weidtkamp-Peters S, Postma M, Zhou W, Goedhart J, Sánchez-Pérez M, Gadella T, Simon R, Scheres B and Blilou I^#. (2017). In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots. Nature, 548: 97–102. doi: https://doi.org/10.1038/nature23317.

16. Li H, Torres-Garcia J, latrasse D, Benhamed M, Schilderink S, Zhou W, Kulikova O, Hirt H and Bisseling T^#. (2017). Plant-specific histone deacetylases HDT½ regulate GIBBERELLIN 2-OXIDASE 2 expression to control Arabidopsis root meristem cell number. Plant Cell, 29:2183-2196. doi: https://doi.org/10.1105/tpc.17.00366.

17. Kang J, Yu H, Tian C, Zhou W, Li C, Jiao Y, Liu D^#. (2014). Suppression of   photosynthetic gene expression in roots is required for sustained root growth under phosphate deficiency. Plant Physiol, 165: 1156-1170. doi: https://doi.org/10.1104/pp.114.238725.

18. Yu X, Pasternak T, Eiblmeier M, Ditengou F, Kochersperger P, Sun J, Wang H, Rennenberg H, Teale W, Paponov I, Zhou W, Li C, Li X^#, and Palme K^#. (2013). Plastid-localized glutathione reductase2-regulated glutathione redox status is essential for Arabidopsis root apical meristem maintenance. Plant Cell, 25: 4451-4468. doi: https://doi.org/10.1105/tpc.113.117028.

19. Chen R*, Jiang H*, Li L, Zhai Q, Qi L, Zhou W, Liu X, Li H, Zheng W, Sun J and Li C^#. (2012). The Arabidopsis mediator subunit MED25 differentially regulates jasmonate and abscisic acid signaling through interacting with the MYC2 and ABI5 transcription factors. Plant Cell, 24: 2898-2916. doi: https://doi.org/10.1105/tpc.112.098277.

20. Chen Q*, Sun J*, Zhai Q, Zhou W, Qi L, Xu L, Jiang H, Qi J, Li X, Palme K and Li C^#. (2011). The basic helix-loop-helix transcription factor MYC2 directly represses PLETHORA expression during jasmonate-mediated modulation of the root stem cell niche in Arabidopsis. Plant Cell, 23: 3335-3352. doi: https://doi.org/10.1105/tpc.111.089870.

21. Sun J*, Chen Q*, Qi L, Jiang H, Li S, Xu, Y, Liu F, Zhou W, Pan J, Li X, Palme K and Li C^#. (2011). Jasmonate modulates endocytosis and plasma membrane accumulation of the Arabidopsis PIN2 protein. New Phytol, 191: 360-375. doi: https://doi.org/10.1111/j.1469-8137.2011.03713.x.

22. Sun J, Xu Y, Ye S, Jiang H, Chen Q, Liu F, Zhou W, Chen R, Li X, Tietz O, Wu X, Cohen J, Palme K and Li C^#. (2009). Arabidopsis ASA1 is important for jasmonate-mediated regulation of auxin biosynthesis and transport during lateral root formation. Plant Cell, 21: 1495-1511. doi: https://doi.org/10.1105/tpc.108.064303.

获奖情况

2014 欧盟EMBO长期博士后奖学金

承担项目及课题

2023：国家重点研发计划子课题

2022：国家自然科学基金面上项目

2021：海外高层次人才引进计划青年项目（获优先资助）

2020：国家自然科学基金面上项目